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However, challenges remain in optimizing their cartilage-specific targeting in dense ECM environments, understanding their effects on synovial and subchondral tissues, and validating long-term therapeutic benefits in age-related or metabolic OA models

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This GHSR activation by Ipamorelin may result in increased GH secretion, which, in turn, might promote protein synthesis, lipolysis, and insulin-like growth factor-1 (IGF-1) production, as suggested by researchers

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